Author: Wei Liu1, Xue-Mei Liu2, Ya-Ling Huang3, Peng-Ming Yu4, Xia-Wei Zhang5, Chen Zhao6, Bing Mao7, Jie Min8, Hong-Li Jiang9
Affiliation:
1 Group of Pulmonary Disease, Insitute of Integrated Traditional and Western Medicine, West China Hospital of Sichuan University, Chengdu, P. R. China. Electronic address: liuwei0929@wchscu.cn.
2 Group of Pulmonary Disease, Insitute of Integrated Traditional and Western Medicine, West China Hospital of Sichuan University, Chengdu, P. R. China; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, P. R. China. Electronic address: xuemei.liu@wchscu.cn.
3 Group of Pulmonary Disease, Insitute of Integrated Traditional and Western Medicine, West China Hospital of Sichuan University, Chengdu, P. R. China. Electronic address: 1319361867@qq.com.
4 Department of Rehabilitation, West China Hospital of Sichuan University, Chengdu, P. R. China. Electronic address: 13438201451@126.com.
5 Respiratory Medicine Unit and National Institute for Health Research, Nuffield, Department of Medicine Experimental Medicine, Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. Electronic address: xiawei.zhang@ndm.ox.ac.uk.
6 Department of Oral Medicine, Stomatological Hospital and Dental School of Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai, P. R. China. Electronic address: tjkqnm@163.com.
7 Group of Pulmonary Disease, Insitute of Integrated Traditional and Western Medicine, West China Hospital of Sichuan University, Chengdu, P. R. China. Electronic address: maobing@medmail.com.cn.
8 Group of Pulmonary Disease, Insitute of Integrated Traditional and Western Medicine, West China Hospital of Sichuan University, Chengdu, P. R. China.
9 Group of Pulmonary Disease, Insitute of Integrated Traditional and Western Medicine, West China Hospital of Sichuan University, Chengdu, P. R. China. Electronic address: annabel_mj@163.com.
Conference/Journal: Complement Ther Med
Date published: 2023 Aug 23
Other:
Special Notes: doi: 10.1016/j.ctim.2023.102977. , Word Count: 287
Objectives:
With the characteristics of mindfulness and breathing techniques, Tai Chi has been recommended with therapeutic values in chronic obstructive pulmonary disease (COPD). However, its strengths as a complementary exercise for conventional pulmonary rehabilitation (PR) remain unclear.
Design and setting:
This single-blinded randomised controlled trial recruited patients with mild to severe stable COPD. Eligible participants were randomly assigned to the group with usual care (control), total body recumbent stepper (TBRS) exercise, Tai Chi (TC), or combined TBRS exercise and Tai Chi (TBRS-TC). Patients received a two-month hospital-based supervised exercise, followed by a ten-month community- or home-based rehabilitation program.
Results:
A total of 120 participants were recruited, and 102 were included in the per-protocol analysis. The mean changes in St George's Respiratory Questionnaire (SGRQ) total score from baseline to the post-hospital exercise in the control group, TBRS group, TC group, and TBRS-TC group was 2.62 (95% CI -8.99 to 8.99), -9.28 (95% CI -13.96 to -4.60), -10.19 (95% CI -13.72 to -6.67), and -16.75 (95% CI -20.25 to -13.24), respectively, with a statistically significant difference between groups in favor of the TBRS-TC exercise (P < 0.001). The remarkable effect of TBRS-TC exercise in improving the qualtiy of life maintained until the end of the community- or home-based rehabilitation training (P < 0.001). Besides, a statistically better effect with the TBRS-TC exercise was also observed in the outcomes regarding exercise capacity, pulmonary function, symptom burden, and systemic inflammation after the whole process of 12-month integrative PR exercise programme.
Conclusions:
Based on the results, a novel integrated exercise modality combining Tai Chi and conventional pulmonary rehabilitation was developed. It might contribute to more positive effects in patients with stable COPD.
Keywords: Chronic Obstructive Pulmonary Disease; Integrated Rehabilitation Exercise Modality; Pulmonary Rehabilitation; Randomised Controlled Trial; Tai Chi.
PMID: 37625624 DOI: 10.1016/j.ctim.2023.102977
