Effect of Baduanjin exercise on cognitive function in patients with post-stroke cognitive impairment: a randomized controlled trial

Author: Guohua Zheng1, Yuhui Zheng2, Zhenyu Xiong2, Bingzhao Ye2
1 College of Nursing and Health Management, Shanghai University of Medicine & Health Sciences, Shanghai, China.
2 College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Conference/Journal: Clin Rehabil
Date published: 2020 Aug 1
Other: Volume ID: 34 , Issue ID: 8 , Pages: 1028-1039 , Special Notes: doi: 10.1177/0269215520930256. , Word Count: 227

To investigate the effectiveness and safety of Baduanjin training on the cognitive function in stroke survivors with cognitive impairment.

A randomized, two-arm parallel controlled trial with allocation concealment and assessors blinding.

Community centre of Fuzhou city, China.

A total of 48 participants were recruited and randomly allocated into the Baduanjin exercise intervention or control group.

The control group maintained original medication and rehabilitation treatment. The Baduanjin training group received 24-week Baduanjin training with a frequency of three days a week and 40 minutes a day based on original medication and rehabilitation treatment.

Main outcome measures:
The primary outcome was global cognitive function. Secondary outcome measures included the specific domains of cognition (i.e. memory, processing speed, execution, attention and visuospatial ability) and activities daily living.

In total, 41 (Baduanjin n = 22, control n = 19) participants completed 24-week treatment and data collection. Mean differences between groups at 24-week treatment were statistically significant for global cognitive function (MoCA: 2.54 (0.91 to 4.16)), execution (TMT-A: -42.4 (-75.0 to -9.8); TMT-B: -71.3 (-130.6 to -12.1)), memory (immediate recall: 2.11 (0.49 to 3.73); short-term delayed recognition: 2.47 (0.58 to 4.35) and long-term delayed recognition: 1.68(0.18 to 3.17)), attention (response time of alertness: -245.5 (-387 to -104)) and activities of daily living (modified Barthel Index).

Regular Baduanjin training is associated with less loss of cognitive function in patients after stroke.

Keywords: Baduanjin exercise; cognitive impairment after stroke; randomized controlled trial.

PMID: 32517490 DOI: 10.1177/0269215520930256