Music Intervention Approaches for Alzheimer's Disease: A Review of the Literature.

Author: Leggieri M1,2, Thaut MH3, Fornazzari L1,4, Schweizer TA1,2,5, Barfett J1,6, Munoz DG1,2,7, Fischer CE1,2,8
1Keenan Research Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.
2Faculty of Medicine, Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
3Music and Health Research Collaboratory, Faculty of Music, University of Toronto, Toronto, ON, Canada.
4Division of Neurology, Department of Medicine, University of Toronto, Toronto, ON, Canada.
5Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
6Division of Nuclear Medicine, Department of Medical Imaging, St. Michael's Hospital, Toronto, ON, Canada.
7Department of Laboratory Medicine and Pathology, University of Toronto, Toronto, ON, Canada.
8Department of Psychiatry, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Conference/Journal: Front Neurosci.
Date published: 2019 Mar 12
Other: Volume ID: 13 , Pages: 132 , Special Notes: doi: 10.3389/fnins.2019.00132. eCollection 2019. , Word Count: 242

Music interventions have been widely adopted as a potential non-pharmacological therapy for patients with Alzheimer's disease (AD) to treat cognitive and/or behavioral symptoms of the disease. In spite of the prevalence of such therapies, evidence for their effectiveness report mixed results in the literature. The purpose of this narrative review is to investigate the effectiveness of various intervention strategies (music therapy vs. music listening techniques) and music type used in the intervention (individualized vs. non-individualized music) on cognitive and behavioral outcomes for persons with AD. Databases were searched for studies using either active music therapy or music listening techniques over the last 10 years. These studies were in English, included persons with AD dementia, and whose protocol gathered pre- and post-intervention outcome measures. We initially identified 206 papers which were then reduced to 167 after removing duplicates. Further review yielded 13 papers which were extensively reviewed, resulting in a final sample of six papers. Our analysis of these papers suggested that, regardless of the music intervention approach, individualized music regimens provided the best outcomes for the patient. Furthermore, music listening may act as a relaxation technique and therefore provide a long-term impact for the patient, while active music therapy may acts to engage participants through social interaction and provide acute benefits. Our findings suggest that music techniques can be utilized in various ways to improve behavior and cognition.

KEYWORDS: Alzheimer’s disease; cognitive function; music listening; music therapy; music-based intervention

PMID: 30930728 PMCID: PMC6424022 DOI: 10.3389/fnins.2019.00132