Extremely low frequency variable electromagnetic fields affect cancer and noncancerous cells in vitro differently: Preliminary study.
Author: Koziorowska A1,2, Romerowicz-Misielak M2, Sołek P3, Koziorowski M3
Affiliation:
1a Faculty of Mathematics and Natural Sciences , University of Rzeszow , Rzeszow , Poland.
2b Laboratory of Bioelectromagnetism, Institute of Biotechnology , University of Rzeszow , Rzeszow , Poland.
3c Department of Physiology and Reproduction of Animals, Institute of Biotechnology , University of Rzeszow , Rzeszow , Poland.
Conference/Journal: Electromagn Biol Med.
Date published: 2018 Mar 7
Other:
Volume ID: 1-8 , Special Notes: doi: 10.1080/15368378.2017.1408021. [Epub ahead of print] , Word Count: 135
The exposure to extremely low frequency electromagnetic field (ELF-EMF) may result in various changes at the cellular level. To identify the effect of ELF-EMF exposure on viability of cells, cancer cells (U87-MG; 143B) and noncancerous cells (BJ; HEK) in exponential growth phase were exposed or sham-exposed to different values of frequency (2, 20, 30, 50 and 60 Hz), different shapes (sinusoidal, square and triangular) and time of exposure (0.5, 1, 2, 3 h) to electromagnetic field. After exposure, viability of cells was detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). We found a different effect of exposition of cancer and noncancerous cells to ELF-EMF on viability of cells. This preliminary study revealed that electro magentic field(EMF) might serve as a potential tool for manipulating viability of cells.
KEYWORDS: 143B cells; BJ cells; EMF; HEK cells; U87-MG cells; viability
PMID: 29513614 DOI: 10.1080/15368378.2017.1408021
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