Pain Perception Can Be Modulated by Mindfulness Training: A Resting-State fMRI Study.
Author: Su IW1, Wu FW2, Liang KC3, Cheng KY4, Hsieh ST5, Sun WZ6, Chou TL7
Affiliation:
1Graduate Institute of Linguistics, National Taiwan UniversityTaipei, Taiwan; Neurobiology and Cognitive Science Center, National Taiwan UniversityTaipei, Taiwan; Graduate Institute of Brain and Mind Sciences, National Taiwan UniversityTaipei, Taiwan.
2Department of Psychology, National Taiwan University Taipei, Taiwan.
3Neurobiology and Cognitive Science Center, National Taiwan UniversityTaipei, Taiwan; Graduate Institute of Brain and Mind Sciences, National Taiwan UniversityTaipei, Taiwan; Department of Psychology, National Taiwan UniversityTaipei, Taiwan.
4Institute of Philosophy of Mind and Cognition, National Yang-Ming University Taipei, Taiwan.
5Neurobiology and Cognitive Science Center, National Taiwan UniversityTaipei, Taiwan; Graduate Institute of Brain and Mind Sciences, National Taiwan UniversityTaipei, Taiwan; Department of Neurology, National Taiwan University HospitalTaipei, Taiwan.
6Neurobiology and Cognitive Science Center, National Taiwan UniversityTaipei, Taiwan; Graduate Institute of Brain and Mind Sciences, National Taiwan UniversityTaipei, Taiwan; Department of Anesthesiology, National Taiwan University HospitalTaipei, Taiwan.
7Neurobiology and Cognitive Science Center, National Taiwan UniversityTaipei, Taiwan; Department of Psychology, National Taiwan UniversityTaipei, Taiwan.
Conference/Journal: Front Hum Neurosci.
Date published: 2016 Nov 10
Other:
Volume ID: 10 , Pages: 570 , Word Count: 177
The multi-dimensional nature of pain renders difficult a holistic understanding of it. The conceptual framework of pain is said to be cognitive-evaluative, in addition to being sensory-discriminative and affective-motivational. To compare participants' brain-behavior response before and after a 6-week mindfulness-based stress reduction training course on mindfulness in relation to pain modulation, three questionnaires (the Dallas Pain Questionnaire, Short Form McGill Pain Questionnaire-SFMPQ, and Kentucky Inventory of Mindfulness) as well as resting-state functional magnetic resonance imaging were administered to participants, divided into a pain-afflicted group (N = 18) and a control group (N = 16). Our results showed that the pain-afflicted group experienced significantly less pain after the mindfulness treatment than before, as measured by the SFMPQ. In conjunction, an increased connection from the anterior insular cortex (AIC) to the dorsal anterior midcingulate cortex (daMCC) was observed in the post-training pain-afflicted group and a significant correlation was found between AIC-daMCC connectivity and SFMPQ scores. The results suggest that mindfulness training can modulate the brain network dynamics underlying the subjective experience of pain.
KEYWORDS: connectivity; mindfulness; pain; perspective shift; resting-state
PMID: 27891085 DOI: 10.3389/fnhum.2016.00570
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