Effects of mind-body exercise on knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials

Author: Hujun Qiao1,2, Xin Hao3, Guoxiang Wang4
Affiliation:
1 School of Physical Education, Soochow University, Suzhou, 215021, China. qiaohujun123@163.com.
2 Changzhi University, Changzhi, 046000, China. qiaohujun123@163.com.
3 Changzhi University, Changzhi, 046000, China.
4 School of Physical Education, Soochow University, Suzhou, 215021, China. kwang63@163.com.
Conference/Journal: BMC Musculoskelet Disord
Date published: 2024 Mar 22
Other: Volume ID: 25 , Issue ID: 1 , Pages: 229 , Special Notes: doi: 10.1186/s12891-024-07278-4. , Word Count: 245


Objective:
To evaluate the effect of mind-body exercise on improving knee osteoarthritis (KOA) and thereby informing osteoarthritis exercise rehabilitation.

Methods:
The China National Knowledge Infrastructure (CNKI), Wanfang, PubMed/Medline, Cochrane Library, Web of Science, EBSCO, Embase, Scopus, and ProQuest databases were searched to identify randomized controlled trials (RCTs) that involved tai chi, yoga, and baduanjin interventions for KOA. The search period ranged from inception to October 25, 2022. The methodological quality of the included studies was evaluated by the Cochrane risk of bias assessment tool, and the included data were statistically analyzed and plotted using Review Manager 5.3 and Stata 14.0 software.

Results:
We included 17 articles with a total of 1122 patients. Compared with the control group, mind-body exercise significantly improved patient pain (standardized mean difference (SMD) = -0.65, 95% confidence interval (CI) [-0.87, -0.42], p < 0.00001), stiffness (SMD = -0.75, 95% CI [-1.05, -0.45], p < 0.00001), physical function (SMD = -0.82, 95% CI [-1.03, -0.62], p < 0.00001), mental health (SMD = 0.31, 95% CI [0.11, 0.51], p = 0.002), and depression (SMD = -0.32, 95% CI [-0.50, -0.15], p = 0.0003). In terms of motor ability, mind-body exercise significantly increased the 6-min walking distance (SMD = 18.45, 95% CI [5.80, 31.10], p = 0.004) and decreased timed up and go test time (SMD = -1.15, 95% CI [-1.71, -0.59], p < 0.0001).

Conclusions:
The current study showed that mind-body exercise is safe and effective for KOA patients. However, given the methodological limitations of the included studies, additional high-quality evidence is needed to support the conclusions of this study.

Keywords: Baduanjin; Knee osteoarthritis; Meta-analysis; Mind–body exercise; Taichi; Yoga.

PMID: 38515124 PMCID: PMC10958976 DOI: 10.1186/s12891-024-07278-4

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