Author: Tingting Lu1, Honghao Lai2, Hongsheng Lin3, Fei Ma4, Li Hou5, Lili Tang6, Yi Zhu7, Huijuan Mao8, Anthony Lin Zhang9, Myeong Soo Lee10, Akihiko Ozaki11, Mariana Cabral Schveitzer12, Hui Zhao13, Lidan Zhong14, Baohui Jia3, Lei Fan3, Jiajie Huang15, Baojin Han3, Weilong Zhao2, Long Ge2, Jie Liu3, Luqi Huang13,16
Affiliation:
1 Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
2 Evidence-Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, China.
3 Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
4 Cancer Hospital, Chinese Academy of Medical Sciences, Beijing, China.
5 Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
6 Rehabilitation Department, Peking University Cancer Hospital, Beijing, China.
7 Musculoskeletal Pain Rehabilitation diagnosis and Treatment Center, Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
8 School of Acupuncture and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
9 School of Health and Biomedical Sciences, Royal Melbourne Institute of Technology University, Bundoora, Australia.
10 KM Science Research Division, Korea Institute of Oriental Medicine, Daejeon, South Korea.
11 Breast and Thyroid Center, Jyoban Hospital of Tokiwa Foundation, Fukushima, Japan.
12 Departamento de Medicina Preventiva, Escola Paulista de Medicina, Universidade Federal de So Paulo-Unifesp, São Paulo, Brazil.
13 China Center for Evidence Based Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing, China.
14 School of Biological Sciences, Nanyang Technological University, Singapore.
15 School of Nursing, Gansu University of Chinese Medicine, Lanzhou, China.
16 National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Conference/Journal: J Evid Based Med
Date published: 2025 Jun 1
Other:
Volume ID: 18 , Issue ID: 2 , Pages: e70029 , Special Notes: doi: 10.1111/jebm.70029. , Word Count: 263
Aim:
Breast cancer imposes a serious disease and economic burden on patients. This guideline aims to develop a living evidence-based clinical practice recommendations to guide the use of integrative therapies for the improvement of patient-reported outcomes (PROs) in breast cancer survivors.
Methods:
We searched systematic reviews and meta-analyses or conducted de nova systematic reviews and meta-analyses to support the recommendations. The grading of recommendations, assessment, development, and evaluation approach was used to rate the certainty of evidence and the strength of recommendations.
Results:
The guideline panel issued 17 recommendations: for alleviating anxiety, strong recommendations in favor of muscle relaxation training, yoga, acceptance and commitment therapy, cognitive behavioral therapy, psychological education, and Tai Chi in general breast cancer survivors; for alleviating depression, strong recommendations in favor of mindfulness therapy, cognitive behavioral therapy, group psychotherapy, muscle relaxation training, acceptanceand commitment therapy in general breast cancer survivors, and exercise intervention for patients received radiotherapy; for sleep quality, conditional recommendations for all therapies; for pain, strong recommendations in favor of exercise intervention for postoperative breast cancer survivors; for alleviating fatigue, strong recommendations in favor of mindfulness therapy and group psychotherapy in general breast cancer survivors; for improving the quality of life, strong recommendations in favor of mindfulness therapy in general breast cancer survivors, Baduanjin and exercise intervention for patients undergoing anticancer treatment.
Conclusion:
This proposed guideline provides recommendations for improving the PROs of breast cancer survivors. We hope these recommendations can help support practicing physicians and other healthcare providers for breast cancer survivors.
Keywords: breast cancer survivors; clinical practice guideline; integrative therapies; patient‐reported outcomes.
PMID: 40207746 DOI: 10.1111/jebm.70029
