Effects of Tibetan Music on Neuroendocrine and Autonomic Functions in Patients Waiting for Surgery: A Randomized, Controlled Study.

Author: Cotoia A1, Dibello F1, Moscatelli F2, Sciusco A3, Polito P4, Modolo A5, Gallo C2, Cibelli G2, Cinnella G1
Author Information:
1Department of Anesthesia, Intensive Care, and Pain Therapy, University of Foggia, Policlinico "OO. Riuniti", Foggia, Italy.
2Department of Clinical and Experimental Medicine, University of Foggia, Policlinico "OO. Riuniti", Foggia, Italy.
3Department of Intensive Care and Anaesthesia, North Bristol NHS Trust, Bristol, UK.
4Department of Blood Transfusion Medicine, ASS 5 Friuli Occidentale, Pordenone, Italy.
5Naturopathy, A.N.E.A. Academy, Prato, Italy.
Conference/Journal: Anesthesiol Res Pract.
Date published: 2018 Mar 5
Other: Volume ID: 2018 , Pages: 9683780 , Special Notes: doi: 10.1155/2018/9683780. eCollection 2018. , Word Count: 234

Background: The aim of this study was to investigate the effects of listening to Tibetan music on anxiety and endocrine, autonomic, cognitive responses in patients waiting for urologic surgery.

Methods: Sixty patients waiting for surgery were enrolled to the study. They were randomized in music (M) and control (C) groups. The M group listened to a low-frequency Tibetan music for 30 min (T0-T30) through headphones, and the C group wore headphones with no sound. The State Trait Anxiety Inventory Questionnaire (STAI) Y-1 was administered at T0 and T30. Normalized low (LFnu) and high frequencies (HFnu) of heart rate variability, LF/HF ratio, and galvanic skin response (GRS) data were analyzed at T0, T10, T20, T30, and T35. The salivary α-amylase (sAA) samples were collected at T0, T35, and T45.

Results: In the M group, the STAI Y-1 score decreased at T30 versus baseline (p < 0.001), sAA levels decreased at T35 versus T0(p=0.004), and GSR remained unchanged. In the C group, the STAI Y-1 score remained unchanged, sAA level increased at T35 versus T0(p < 0.001), and GSR slightly increased at T35 versus baseline (p=0.359). LFnu was lower, and HFnu was significantly higher (T10-T30) in M versus C group. Mean LF/HF ratio slightly reduced in the M group.

Conclusions: Our results suggest that preoperative listening to relaxing Tibetan music might be a useful strategy to manage preoperative anxiety.

PMID: 29692808 PMCID: PMC5859866 DOI: 10.1155/2018/9683780