Music Therapy in Parkinson's Disease. Author: García-Casares N1, Martín-Colom JE2, García-Arnés JA3 Affiliation: <sup>1</sup>Department of Medicine, Faculty of Medicine, University of Malaga, Malaga, Spain; Centro de Investigaciones Médico-Sanitarias (CIMES), University of Malaga, Malaga, Spain; Instituto de Investigación Biomédica de Málaga (IBIMA), Malaga, Malaga, Spain. Electronic address: nagcasares@uma.es. <sup>2</sup>Department of Medicine, Faculty of Medicine, University of Malaga, Malaga, Spain. <sup>3</sup>Department of Pharmacology, Faculty of Medicine, University of Malaga, Malaga, Spain. Conference/Journal: J Am Med Dir Assoc. Date published: 2018 Dec Other: Volume ID: 19 , Issue ID: 12 , Pages: 1054-1062 , Special Notes: doi: 10.1016/j.jamda.2018.09.025. , Word Count: 269 OBJECTIVES: Parkinson's disease (PD) is a chronic progressive neurologic disorder involving degeneration of the dopaminergic system. Its clinical manifestations include motor and nonmotor symptoms. Several nonpharmacologic therapies, such as music therapy (MT), have recently been developed in order to improve the clinical manifestations of this disease. The aim of this narrative literature review is to analyze the scientific evidence for the therapeutic effects of music in PD. DESIGN: We undertook a search in the databases of PubMed, PsycINFO, Scopus, MEDLINE, and Science Direct. SETTINGAND PARTICIPANTS: Inclusion criteria were articles including persons with PD rehabilitated with an MT intervention. MEASURES: Keywords used were music therapy, Parkinson's disease, auditory cueing, non-motor symptoms, motor symptoms, and quality of life. RESULTS: We detected a total of 27 articles, all of which analyzed the therapeutic effects of MT in PD. Of these, 20 studies analyzed the effects in motor symptoms (16 showed beneficial effects and 4, nonbeneficial effects); 9 studies analyzed the effects in nonmotor symptoms, 7 of which demonstrated beneficial effects; and 8 studies analyzed the effects on quality of life, with 6 reporting benefits. None of the articles analyzing nonmotor symptoms and quality of life showed negative effects. CONCLUSIONS/IMPLICATIONS: Most of the studies analyzed demonstrated that MT has beneficial effects for the nonpharmacologic treatment of motor and nonmotor symptoms and quality of life of persons with PD. The use of music as a therapeutic tool combined with conventional therapies should be taken into account. Copyright © 2018 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved. KEYWORDS: Music therapy; Parkinson's disease; auditory cueing; motor symptoms; nonmotor symptoms; quality of life PMID: 30471799 DOI: 10.1016/j.jamda.2018.09.025