Mindfulness-Based Interventions for Adults Living with HIV/AIDS: A Systematic Review and Meta-analysis.


Author: Scott-Sheldon LAJ1,2,3, Balletto BL4, Donahue ML4, Feulner MM4, Cruess DG5, Salmoirago-Blotcher E4,6,7, Wing RR4,8, Carey MP4,8,9

Affiliation: <sup>1</sup>Centers for Behavioral and Preventive Medicine, The Miriam Hospital, CORO Building, Suite 309, 164 Summit Avenue, Providence, RI, 02906, USA. lori_scott-sheldon@brown.edu.

<sup>2</sup>Department of Psychiatry and Human Behavior, Alpert School of Medicine, Brown University, Providence, RI, USA. lori_scott-sheldon@brown.edu.

<sup>3</sup>Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA. lori_scott-sheldon@brown.edu.

<sup>4</sup>Centers for Behavioral and Preventive Medicine, The Miriam Hospital, CORO Building, Suite 309, 164 Summit Avenue, Providence, RI, 02906, USA.

<sup>5</sup>Department of Psychological Sciences, University of Connecticut, Storrs, CT, USA.

<sup>6</sup>Department of Medicine, Alpert School of Medicine, Brown University, Providence, RI, USA.

<sup>7</sup>Department of Epidemiology, Brown University School of Public Health, Providence, RI, USA.

<sup>8</sup>Department of Psychiatry and Human Behavior, Alpert School of Medicine, Brown University, Providence, RI, USA.

<sup>9</sup>Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI, USA.
Conference/Journal: AIDS Behav.
Date published: 2018 Jul 27
Other:
  Special Notes: doi: 10.1007/s10461-018-2236-9. [Epub ahead of print]   ,  Word Count: 175  
    This meta-analysis examined the effects of mindfulness-based interventions (MBIs) on stress, psychological symptoms, and biomarkers of disease among people living with HIV/AIDS (PLWHA). Comprehensive searches identified 16 studies that met the inclusion criteria (N = 1059; M age = 42 years; 20% women). Participants had been living with HIV for an average of 8 years (range = < 1-20 years); 65% were currently on antiretroviral therapy. Between-group analyses indicated that depressive symptoms were reduced among participants receiving the MBIs compared to controls (d+ = 0.37, 95% CI 0.03, 0.71). Within-group analyses showed reductions in psychological symptoms (i.e., less anxiety, fewer depressive symptoms) and improved quality of life over time among MBI participants (d+s = 0.40-0.85). No significant changes were observed for immunological outcomes (i.e., CD4 counts) between- or within-groups. MBIs may be a promising approach for reducing psychological symptoms and improving quality of life among PLWHA. Studies using stronger designs (i.e., randomized controlled trials) with larger sample sizes and longer follow-ups are needed to clarify the potential benefits of MBIs for PLWHA.



KEYWORDS: HIV; Intervention; Meta-analysis; Mindfulness; Systematic review



PMID: 30054765  DOI: 10.1007/s10461-018-2236-9