Sensory-motor training versus resistance training among patients with knee osteoarthritis: randomized single-blind controlled trial. Author: Gomiero AB1, Kayo A2, Abraão M1, Peccin MS1, Grande AJ3, Trevisani VF4 Affiliation: <sup>1</sup>MSc. Physiotherapist, Department of Medicine, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil. <sup>2</sup>PhD. Physiotherapist, Department of Medicine, Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil. <sup>3</sup>PhD. Associate Professor, Department of Medicine, Universidade Estadual de Mato Grosso do Sul (UEMS), Campo Grande (MS), Brazil. <sup>4</sup>MD, PhD. Associate Professor, Department of Medicine, Universidade Federal de São Paulo (UNIFESP), and Full Professor, Discipline of Reumatology, Universidade de Santo Amaro (UNISA), São Paulo (SP), Brazil. Conference/Journal: Sao Paulo Med J. Date published: 2018 Jan-Feb Other: Volume ID: 136 , Issue ID: 1 , Pages: 44-50 , Special Notes: doi: 10.1590/1516-3180.2017.0174100917. Epub 2017 Dec 7. , Word Count: 231 BACKGROUND: Osteoarthritis of the knee is defined as a progressive disease of the synovial joints and is characterized by failure of joint damage repair. The objective here was to compare the effectiveness of sensory-motor training versus resistance training among patients with knee osteoarthritis. DESIGN AND SETTING: Randomized, single-blinded controlled trial conducted at the outpatient service of the University of Santo Amaro. METHODS: A total of 64 patients were randomly assigned to sensory-motor training or resistance training. The evaluations were performed at baseline and 16 weeks after the intervention and included pain evaluation on a visual analogue scale, isometric quadriceps femoris force measurement using a dynamometer, Timed Up and Go test, Tinetti balance scale, Western Ontario and McMaster Universities osteoarthritis index, and the SF-36 quality-of-life questionnaire. Data analysis was performed using analysis of variance with repeated measurements and Cohen's effect size. RESULTS: Sensory-motor training may be a plausible alternative and showed a small effect on pain and a medium effect on maximal voluntary isometric contraction. Resistance training showed a small effect on balance and a medium effect on mobility. CONCLUSION: Resistance training and sensory motor training for the lower limbs among patients with knee osteoarthritis seemed to present similar effects on pain and function. However, because there was a considerable risk of type 2 error, further randomized clinical trials are still needed to provide a sound conclusion. TRIAL REGISTRATION: ClinicalTrials.gov NCT01529398. PMID: 29236934 DOI: 10.1590/1516-3180.2017.0174100917